Reta M® is the first hypromellose/mannitol-based, co-processed excipient specifically designed for DC and dry granulation of modified release formulations. To minimize development time, API dissolution prediction as a function of tablet geometry is possible. This is aided by Reta M®’s dramatic improvement in wettability compared to HPMC alone or in traditional wet granulations and simple admixtures.
MEGGLEs co-processed excipient, Reta M®, appears as a white, or almost white odorless powder, which is freely flowing and partially soluble in cold water. It comprises equal parts of hypromellose (HPMC) with a nominal viscosity of 4000 mPa·s, together with Mannitol.
Shelf life / Retest:
15 kg - Carton box with PE-EVOH-PE-Inliner